The Detectors research stream aims to explore new applications of the RaII detectors. It is also supporting translation and commercialisation activity around the detectors. The team is eagerly anticipating the release of a new detector in 2022.

Key people:

Inverted Kronoscan system

A new inverted Kronoscan system with live cell imaging functionality was built in 2021. Current research is using brain slice imaging to explore possibilities for early diagnosis of Parkinson’s and Alzheimer’s. Next steps include developing applications of spectral time-resolved Fluorescence Resonance Energy Transfer (FRET).

Inverted Kronoscan

The Durham team is testing the LightOx probes with the inverted system to investigate the potential for photodynamic therapy.

Relevant publication:

Device location

The RaII detectors have been integrated into a camera system for clinical use, with the intention to use widefield single-photon imaging for locating devices in the body. Relevant publications:

The Detectors team and Endocam team are working together on widefield time-resolved fluorescence imaging during open surgery to help surgeons assess cancer margins.

Further work on time-resolved fluorescence spectroscopy is also underway. Relevant publications:


Through academic collaborations, other groups in the UK are evaluating the RaII sensors, and we are continuing to explore a variety of commercial applications.